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99% Purity Phenacetin Pain Relief Raw Powder CAS 94-24-6 For Pain-Relieving Factory Supply

99% Purity Phenacetin Pain Relief Raw Powder CAS 94-24-6 For Pain-Relieving Factory Supply

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Product Details:

Place of Origin: China
Brand Name: RAWSGEAR
Certification: ISO9001
Model Number: 62-44-2

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: Aluminum foil packaging
Delivery Time: 3-5 work days
Payment Terms: T/T, Western Union, MoneyGram, Bitcoins
Supply Ability: Mass in stock
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Detailed Product Description
Product Name: Phenacetin Appearance: White Crystalline Powder
MF: C10H13NO2 MW: 179.2157

 

99% Purity Phenacetin Pain Relief Raw Powder CAS 94-24-6 For Pain-Relieving Factory Supply

 

 

Quick details:

 

Name:Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157
Density: 1.099g / cm3
Melting point: 133-138 ℃
Boiling point: 355.1 ° C at 760 mmHg
Flash Point: 168.5 ° C
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 ° C
Usage: Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.

 

 

 

Description:

 

Phenacetin is an analgesic, once widely used; its use has declined because of its adverse effects, some of which are described in the following.Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.

 

The painkiller phenacetin was the worlds first synthetic pharmaceutical drug. It was developed by an American chemist and began distribution in 1887. Phenacetin was often accompanied by aspirin and caffeine in what were called APC pills, which were widely distributed during and after World War II. The use of phenacetin in the U.S. was discontinued in the 1980s because of links to cancer and other adverse side effects, but it remains available in some countries.


Phenacetin is a white crystalline powder with the chemical composition C10H13NO2. It was first developed by Harmon Northrop Morse in 1878. In addition to its pain-reducing properties, it also has been used as a fever-reducer, a treatment for rheumatoid arthritis and a treatment for intercostal neuralgia, a rare disorder that causes pain in the nerves around the ribs. It was one of the first painkillers that was not derived from opium while at the same time being absent of anti-inflammatory qualities.

 

 

 

Phenacetin Usage:


It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the etherification, reduction and Acetylation reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever, headache, neuralgia and other drugs as a compound agent.


Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor makes phenacetin not to be converted into paracetamol, still showed obvious antipyretic effect, thus the antipyretic effect after the product line does not converge to paracetamol.The mild phenacetin analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.

 

 

COA:

 

Product name Phenacetin
CAS 62-44-2 Outer Packing 25KGS
Production date 2016.12.27 Shelf life 2019.12.26
Standard adopted BP68
Items of analysis Specification Results
Description Should comply with the standard Comforms
Identification Positive Positive
Melting point 134℃ to 136.5℃ 134.5℃ to 136.5℃
4-chloroacetanilide BP1968 <3.5ml/0.6g
P-Phenetidine BP1968 Comforms
Sulphated ash ≤0.1% 0.07%
Assay ≥99% 99.1%
Through a uss#80   98%
Conclusion Quality

 

 

99% Purity Phenacetin Pain Relief Raw Powder CAS 94-24-6 For Pain-Relieving Factory Supply

 

Applications:


Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincents APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).


It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roches Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetins carcinogenicity.
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

 

 

Local Anesthetic powder

 

Product name CAS No.
Benzocaine 94-09-7
Benzocaine Hcl 137-58-6
Dyclonine Hydrochloride 23964-57-0
Levobupivacaine Hydrochloride 536-43-6
Propitocaine hydrochloride 27262-48-2
Proparacaine hydrochloride 1786-81-8
Ropivacaine Mesylate 854056-07-8
Tetracaine Hydrochloride 136-47-0
Tetracaine base 94-24-6
Prilocaine 721-50-6
Prilocaine Hcl 1786-81-8
Tetracaine (dicain) 94-24-6
Tetracaine Hcl 136-47-0

 

 

Our advantages:


1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
and we have stock in there for transferring.
3,We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers

 

 

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Contact Details
Wuhan Shuiyixing Pharmaceutical Chemical Co., Ltd.

Contact Person: Miss. Gayle

Tel: +8615711952876

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