|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||Foil bag and Disguised bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
Pirfenidone For Inhibit the Uterine Flesh Tumour Cells and Leiomyoma Cells Proliferation
|Pirfenidone Assay(as dried)||99%min|
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice.
Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
In Europe, pirfenidone is indicated for the treatment of mild to moderate idiopathic pulmonary fibrosis. It was approved by the European Medicines Agency in 2011.  In October 2008, it was approved in Japan, in India in 2010 and in China in 2011 (commercial use in 2014). In October 2014, the product was approved for sale in the United States.
In Mexico, it has been approved for the treatment of scars and fibrotic tissue in the form of gel   and has been shown to be effective in treating skin ulcers.
How to use this medicine?
Pirfenidone is administered orally in capsule form. Usually eat three meals a day. Pirfenidone capsules are taken at approximately the same time each day. Follow the instructions on the prescription label carefully and ask the doctor or pharmacist to explain any parts that you do not understand. Take pirfenidone exactly as directed. Do not take it more or less, and do not take more than the doctor's prescribed time.
Your doctor will start using low doses of pirfenidone and gradually increase your dose within 2 weeks.
If you experience some serious side effects, your doctor may need to reduce the dose or stop treatment. Be sure to tell your doctor what you feel during the treatment.
Ask your pharmacist or doctor for a copy of the manufacturer's manufacturer information.
What should I know about the storage and disposal of this drug?
Place the drug in an incoming container, sealed and out of reach of children. Store it at room temperature and keep away from excess heat and moisture (not in the bathroom)
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