19-Carbon Steroid Hormone Powder 4-Androstenedione For Control Infectious Inflammation

19-Carbon Steroid Hormone Powder 4-Androstenedione For Control Infectious Inflammation

4-Androstenedione, popularly known as Androstenedione or 4-AD, has many other names. The synonyms of 4-Androstenedione include 17-ketoestosterone, Andro, Androstene,Androst-4-ene-3,17-dione,4-Androstene-3,17-dione, 4-Androstenedione, Androtex, 63-05-8, 3,17-Dioxoandrost-4-ene, Fecundin,4-AD,SKF 2170 etc. If you are not sure whether it is 4-Androstenedione, make sure that there is only one CAS number for it, and it is 63-05-8.

According to Wikipedia, 4-Androstenedione is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the oestrogens oestrone and oestradiol. 4-Androstenedione originates either from the conversion of dehydroepiandrosterone (DHEA) or from 17- hydroxyprogesterone. Conversion of dehydroepiandrosterone to androstenedione requires 3-ß-hydroxysteroid dehydrogenase. 17- hydroxyprogesterone, on the other hand, requires 17, 20 lyase for its synthesis. Thus, both reactions that produce androstenedione directly or indirectly depend on 17, 20 lyase. 4-Androstenedione is further converted to either testosterone or oestrogen. Conversion of 4-androstenedione to testosterone requires the enzyme 17ßhydroxysteroid dehydrogenase, while conversion of androstenedione to oestrogen (e.g. oestrone and oestradiol) requires the enzyme aromatase. The production of adrenal androstenedione is governed by ACTH(Adrenocorticotropic Hormone), whereas production of gonadal androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total androstendione .

Anabolic steroids are commonly utilized to treat people who have a hormone deficiency or who have muscle wasting due to cancer or HIV. They have also been utilized as performance enhancing drugs to increase muscle strength and size for competitive sports. Supplements containing androstenedione were introduced in the mid 1990’s and were promoted as a natural way to help increase strength and muscle mass and to combat the effects of the aging process in older men, much of which is attributed to declining testosterone levels. Like DHEA, androstenedione is a naturally derived precursor to testosterone.

Applications of 4-androstenedione :

Androstenedione is a steroid hormone. It is used to make medicine.
Androstenedione is the common precursor of male and female sex hormones. Some Androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.
Androstenedione is used to increase the production of the hormone testosterone to enhance athletic performance, increase energy, keep red blood cells healthy, enhance recovery and growth from exercise, and increase sexual desire and performance.
Androstenedione gained popularity as the supplement used by the baseball homerun hitter Mark McGwire and other professional sports players. In January 2005 legislation went into effect in the United States called the Anabolic Steroid Control Act of 2004. This reclassifies androstenedione from a dietary supplement to an anabolic steroid, which is a schedule III controlled substance.
It is used by the body to make testosterone and estrogen.

The dosage and effect of Androstenedione :

4-Androstenedione has been shown to increase serum testosterone levels over an eight-hour period in men when taken as a single oral dose of 300 mg per day, but a dose of 100 mg had no significant effect on serum testosterone. However, serum levels of estradiol increased following both the 100 mg and 300 mg doses.

The study also reported that the serum level of estrogens and testosterone produced varied widely between individuals.Because androstenedione can be converted to estrogenic steroids, people taking this supplement may have estrogenic side-effects.In child development, higher levels of androstenedione in boys have been associated with higher levels of acting out behaviors.

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