|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||Foil bag and Disguised bag|
|Delivery Time:||3-5 work days|
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|Melting Point:||173-179ºC||Boiling Point:||584.543ºC At 760mmHg|
Sarms Powder GW501516 GSK-516 Cardarine For Treat Obesity And Heart Health Problems 317318-70-0
|Product name||GW501516 (GSK-516,Cardarine)|
GW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR delta regulator. GW 501516 activates AMP-activated protein kinases and stimulates glucose uptake in skeletal muscle tissue, GW 501516 has been shown to reverse the metabolic abnormalities of obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. Potential treatments for obesity and related disorders have been proposed, particularly when used in conjunction with the synergistic compound AICAR, since the combination has been shown to significantly enhance exercise tolerance in animal studies.
GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol) are PPARδ receptors. It activates the same pathway through exercise activation, including PPARδ and AMP-activated protein kinases. Has been investigated for potential treatments for obesity, diabetes, dyslipidemia and cardiovascular disease. When combined with AICAR, GW501516 has a synergistic effect: it has been shown that the combination significantly increases exercise tolerance in animal studies compared to the use of compounds alone.
GW501516 is a selective agonist (activator) of the PPAR delta receptor. PPARδ with PPARα and PPARγ with & gt; 1000-fold selectivity showed high affinity (Ki = 1 nM) and titer (EC50 = 1 nM).
In rats, the combination of GW501516 and PPAR delta recruited the auxiliary activator PGC-1a. PPARδ / coactivator complex regulates the expression of proteins involved in energy consumption. In addition, in rats treated with GW501516, the increase in fatty acid metabolism and diet-induced obesity and type II diabetes were observed in skeletal muscle. In obese rhesus monkeys, GW501516 increased high density lipoprotein (HDL) and reduced very low density lipoprotein (VLDL). PPAR delta agonists increase the HDL mechanism as appears to be the result of increased expression of cholesterol transporter ABCA1.
Athletes can use the GW501516 as a sensitizing performance-enhancing drug that has not yet been tested by regulatory or standard testing. One of the leading researchers in the study emphasizes endurance research is to conduct urine tests to detect drugs and provide them to the IOC.
GW1516 is known by many names, including cardarine and endurobol, as well as various iterations of the initials and numbers (e.g., GW501516). Often advertised as a selective androgen receptor modulator (SARM), GW1516 is actually a peroxisome proliferated-activated receptor d (PPARd ) agonist. Substances in this category modify how the body metabolizes fat and GW1516 was originally synthesized and evaluated for the treatment of obesity, diabetes, and other disorders caused by metabolic problems.
GW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR delta regulator. GW 501516 activates AMP-activated protein kinases and stimulates glucose uptake in skeletal muscle tissue, GW 501516 has been shown to reverse the metabolic abnormalities of obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.
GW 501516 very popular and very effective. Its impact on increased endurance and fat loss is surprising. The recommended dose for GW is 10-20 mg for 8 weeks. GW has shown dramatic effects with almost no side effects. It is the favorite of many users and offers a lot of benefits.
Cardarine is mainly used to treat obesity, diabetes, lipid and heart health problems. In fact, those who work with blood will notice that kiwi will magically help with lipids and that their cholesterol levels will increase significantly.
Cardarine is used by athletes for many different sports competitions. For example, endurance athletes can increase exercise tolerance by stacking the PPAR with the AMP analog drug AICAR, or by running kiwi solo. As a result, they will have greater ability to achieve higher RPMs during operation without reaching the maximum heart rate. This will allow runners / cyclists / swimmers to deceive their maximum heart rate and will not be wound for a long time, making it an incredible weapon for use in endurance. In fact, from the personal experience, if used in the game, we can see that monkeys can be more than 5-45 seconds in the time of 30-45 seconds.
About bodybuilders, kiwi can benefit them in two ways
Its ability to burn fat
It can help athletes have more exercise and longer exercise, without winding.
In obesity, by stimulating the oxidation of fatty acids, macaques reversed obesity and pre-diabetes mellitus metabolic abnormalities. That is, it burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body's metabolism and burns fat rather than muscle or carbohydrates. Incredibly, it does not reduce blood sugar levels like diabetes. Interestingly, when mice are given a high fat diet, they still lose fat, which proves that cocaine can prevent obesity.
There are some ways to stack stack card
1.Endurance: I recommend using AICAR and / or Equipoise to stack kiwi. This is the ultimate endurance pile that turns you into a horse.
2. Fat Loss: The best crushing stack will stack Kiwi with S4 (Andarine). This is a well known powerful "cutting" stack.
3. Synthetic metabolic steroid heap: If you run moderate doses of anabolic steroids, or you run any harsh compound like trenbolone, then cardarine will aid in not only your lipids, but also with your ability to 'catch your wind.' Therefore, cardarine is a perfect stack for trenbolone, which makes many athletes lose their breath fast.
4. During PCT (post cycle therapy) or bridge: Since cardarine is not hormonal, it is in no way suppressive. Hence, you should not be scared of using it to keep fat off and improve your workouts between cycles during your bridge and PCT .
5. SARMs triple stack: If you want to recomp, cardarine stacks beautifully with S4 and MK-2866.
GW 501516 can be ran in 8 week cycles, but as with any other steroid or supplement, it should be cycled properly to avoid any possible side effects and the keep it as effective as possible.
The first and most common use is that of increased endurance. Anyone want a drastic increase in endurance will find that GW501516 truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.
The second common usage with GW is that of fat loss. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat. It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.
The half life of cardarine is 20-24 hours. This means that once a day dose is totally fine. Some athletes like to use all the 20 mg an hour before their workout session, and others will split the dose in half in the AM and PM.
It is best to squirt the liquid into your mouth, swallow, and then chase down with some juice or water.
Speciafications of Gw501516 powder
|Appearance||light yellow powder||Complies|
|Related substance (HPLC)||
Total impurity ≤0.5%
Max single impurity ≤0.1%
|Sieve analysis||100% pass 80 mesh||Complies|
Loss on Drying
Residue on Ignition
|Total Plate Count||<1000cfu/g||Complies|
|Yeast & Mold||<100cfu/g||Complies|
(1)GW501516 (GW1516 or GSK-516) is a drug that acts as a PPARδ modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.
(2)GW 501516 is extremely popular and is extremely effective. The effects it has on increased endurance and fat loss have been staggering. The recommended dosage for GW is 10-20 mg and for 8 weeks length. GW has shown to have drastic effects and little to no side effects. It is a favorite amongst many users and offers several great benefits.
What are the benefits of Cardarine
1.Cardarine Protects the Brain
2.Cardarine Benefits the Heart
3.Cardarine Increases Metabolism and Prevents Obesity
4.Cardarine Protects the Kidneys
5.Cardarine Helps the Immune System
6.Cardarine Protects Against Liver Damage
7.Cardarine Improves Muscle Growth and Stamina
8.Cardarine May Help Heal Skin Diseases
9.Cardarine May Improve Blood Flow and Wound Healing
10.Cardarine Has Antioxidant and Anti-inflammatory Potential
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