|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||Foil bag and Disguised bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
Popular Estrogen Drug Ethynylestradiol EE For Treatment of Irregular Menstruation CAS 57-63-6
|Melting point||182-183 °C(lit.)|
|Boiling point||378°C (rough estimate)|
What is Ethynylestradiol (EE)?
Ethynylestradiol (EE) is an estrogen drug that is widely used in birth control pills in combination with progestogens. It is also used together with menopausal hormones as part of menopause hormone therapy to treat menopausal symptoms. In the past, EE has been widely used in a variety of indications, such as the treatment of gynecological diseases and prostate cancer. Usually taken through the mouth.
EE is an agonist of estrogen or estrogen receptor, a biological target of estrogens such as estradiol. This is a synthetic derivative of estradiol, a natural estrogen, and a variety of ways from its differences. Compared with estradiol, EE has a much higher bioavailability when administered orally, is more resistant to metabolism, and shows a relatively enhanced effect in certain parts of the body, such as the liver and uterus. These differences make EE more suitable for contraceptive use than estradiol, although it also leads to an increased risk of thrombosis and some other rare side effects.
EE was developed in the 1930s and was introduced into medical use in 1943. The drug began to be used as a contraceptive in the 1960s. Today, EE is found in almost all combinations of contraceptives and is almost the only estrogen used for this purpose, making it one of the most widely used estrogens.
Ethynylestradiol (EE) Usage:
EE has many uses. This is the most commonly used combination of oral contraceptives (COC), also known as birth control, to prevent pregnancy after sex. EE's birth control formula can be used not only to prevent pregnancy, but also to treat irregular menstruation, symptoms during menstruation and acne.
EE is also used as a hormonal treatment for menopause. The main reason for the use of HRT in menopausal women is to relieve common vasomotor symptoms such as hot flashes, night sweats and flushing. The study found that estrogen replacement helps to improve these symptoms compared with placebo. Other common menopausal symptoms, such as vaginal dryness (which can cause pain during sexual intercourse), vaginal itching and depression, can benefit from HRT. In addition to treating menopausal symptoms, EE is also used as part of a female hormone therapy for degenerative women.
EE can also be used to treat female hypogonadism, prevent osteoporosis in women, and has been used as a palliative treatment for male prostate cancer and female breast cancer.
Because of the increased risk of endometrial cancer, women with uterine cancer are prohibited from using EE or any estrogen alone; taking progesterone together with estrogen can reduce the risk.
Common side effects of EE include breast tenderness, swelling, headache, retention of body fluids, and nausea. In men, EE can also cause breast development, feminization, hypogonadism, and sexual dysfunction. Rare but serious side effects include blood clots, liver damage and uterine cancer.
Ethynylestradiol EE Powder:
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